Physician-Supervised
Peptide Therapy Protocols

Six stacks. One system. Each protocol is biomarker-guided, prescription-based, and built for a specific category of performance. All require physician evaluation before initiation.

Build Brain Bounce Back Boost Weight Management Aesthetics

Performance & Strength

BUILD

Body composition, muscle development, and physical output, calibrated to your biology, not a training template.

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Who this is for

The BUILD stack is designed for athletes, competitive lifters, and anyone serious about optimizing body composition and physical performance. It's relevant both for those building toward a peak and for those who feel their training-to-recovery ratio has shifted over time.

This protocol is particularly effective for individuals in their 30s and 40s who are training consistently but experiencing diminishing returns, slower recovery, reduced strength gains, or body composition plateaus that don't respond to training adjustments alone.

What the protocol addresses

  • Muscle protein synthesis and nitrogen retention
  • Tissue repair and recovery between training sessions
  • Growth hormone axis support
  • Inflammation and overtraining management
  • Body composition (lean mass vs. adipose ratio)

How it works

The BUILD protocol begins with a baseline lab panel reviewing hormone levels, inflammatory markers, metabolic function, and nutritional status. Physician review of your labs, training history, and goals determines the specific protocol design.

Protocols are peptide-based, prescription compounds that signal specific biological pathways. They are not anabolic steroids. They work by optimizing the body's own systems rather than overriding them. All compounds are compounded to pharmaceutical standards.

What to expect

  • Most members notice improved recovery within 3–6 weeks
  • Changes in body composition are typically measurable at 8–12 weeks
  • Sleep quality and energy often improve as secondary benefits
  • Progress is tracked through follow-up labs and clinical check-ins
All BUILD protocols require physician evaluation and a current lab panel before initiation. Protocols are not appropriate for everyone and are contraindicated in certain clinical situations. Your physician will review your eligibility as part of the intake process.

Cognitive Performance

BRAIN

Focus, memory consolidation, and neural resilience, for professionals who need sustained cognitive performance.

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Who this is for

The BRAIN stack is designed for executives, surgeons, attorneys, entrepreneurs, and other high-demand professionals who rely on sharp cognition and are experiencing fatigue, brain fog, or declining mental sharpness that interferes with performance.

It's also appropriate for those who are managing high cognitive load over extended periods and want proactive support, not reactive treatment.

What the protocol addresses

  • Focus and sustained attention under load
  • Memory encoding and recall
  • Neural resilience and neuroprotection
  • Cortisol dysregulation contributing to cognitive fatigue
  • Sleep architecture (which directly impacts cognitive function)

How it works

The BRAIN protocol starts with a lab panel evaluating thyroid function, cortisol patterns, inflammatory markers, nutritional deficiencies, and hormones with known cognitive effects. The clinical assessment also includes a review of your sleep patterns, stress load, and cognitive history.

Peptide-based interventions are selected based on the specific pattern identified, there is no single BRAIN formula. The protocol targets your particular picture of cognitive underperformance.

What to expect

  • Improvements in focus and mental clarity often noted within 2–4 weeks
  • Sleep quality improvements (when addressed) are often reported early
  • Sustained effects depend on protocol adherence and follow-up optimization
  • Objective tracking via follow-up labs at 90 days
Cognitive symptoms can have multiple causes, some of which require clinical workup before peptide therapy is appropriate. The intake process is designed to identify these and ensure you're receiving the right intervention.

Recovery & Resilience

BOUNCE BACK

Accelerated recovery from injury, overtraining, or surgical procedures, physician-managed and lab-informed.

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Who this is for

The BOUNCE BACK stack is appropriate for athletes recovering from musculoskeletal injuries, individuals post-surgery seeking to accelerate healing, and those managing the cumulative damage of high-volume training over years.

This protocol is also used by professionals who experience cyclical overtraining, those who push hard for extended periods and then struggle to fully recover between training blocks.

What the protocol addresses

  • Soft tissue repair (tendons, ligaments, muscle)
  • Systemic and local inflammation
  • Post-surgical healing support
  • Gut integrity (often compromised in overtraining)
  • HPA axis dysregulation from chronic overtraining

How it works

Recovery peptides work through signaling pathways that modulate inflammation, stimulate tissue repair, and support the body's regenerative processes. They are not anti-inflammatory drugs; they work by activating repair mechanisms rather than suppressing immune function.

The specific protocol is tailored to the nature of the injury or recovery challenge identified in your intake and lab review. Surgical clearance may be required for post-operative use.

What to expect

  • Tissue healing timelines vary significantly by injury type and severity
  • Reduction in localized pain and swelling often noted within 2–4 weeks
  • Most effective when combined with appropriate physical therapy
  • Follow-up imaging or labs assess objective recovery progress
BOUNCE BACK protocols are not a substitute for standard-of-care medical treatment. They are intended as an adjunct to established recovery protocols under physician supervision. Post-surgical use requires coordination with your surgical team.

Energy & Mental Clarity

BOOST

A structured cognitive sprint — intranasal peptides for focus, clarity, and mental resilience during high-demand periods.

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Who this is for

The BOOST stack is designed for periods of intense cognitive demand — heavy clinical schedules, research blocks, high-stakes administrative work, or any stretch where mental output needs to stay high and fatigue needs to stay low. It’s also used as a short-term intervention for folks experiencing post-viral cognitive dulling, stress-related fog, or reduced mental resilience.

This is a situational protocol — a 4-week cycle intended for strategic use, not permanent daily supplementation. Think of it as a structured cognitive sprint, not a new baseline.

What the protocol addresses

  • Mental fog and reduced focus during high-demand periods
  • Anxiety and nervous system hyperactivation under cognitive load
  • Cognitive processing speed and working memory
  • Neurotrophic and vascular support within the brain

How it works

The BOOST stack is entirely intranasal, no injections. Three peptides are delivered as nasal sprays, making this one of the most accessible protocols in the Kinetic Edge suite. Semax drives focus and processing speed through BDNF upregulation. Selank provides GABAergic stabilization, keeping performance sharp without the edge turning into jitter. GHK-Cu works in the background to support healthy vascular signaling and neurotrophic activity.

The combination produces a state of alert calm, productive without being overstimulated. The protocol runs as a 4-week cycle followed by a 2-week off period. No more than two consecutive cycles without physician reassessment.

What to expect

  • Improved focus and reduced mid-day cognitive slump, often within the first week
  • Alert calm, productive without overstimulation
  • GHK-Cu effects are subtler, accumulating over the cycle rather than presenting acutely
  • If headache, nasal irritation, or overstimulation occurs, your physician can adjust the protocol
BOOST is a situational protocol, not a long-term daily intervention. If your primary concern is chronic fatigue, low drive, or hormonal imbalance, your physician may recommend a different protocol better suited to those goals. The intake process ensures the right match before any intervention begins.

Metabolic Health

WEIGHT MANAGEMENT

Physician-supervised metabolic support, biology-first, not a calorie restriction template.

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Who this is for

The Weight Management protocol is for individuals who have struggled with body composition despite consistent effort, those who are doing "everything right" and still not seeing results, or those who have significant weight loss goals that have not responded to conventional approaches.

This is not a general wellness program. It requires physician oversight, lab work, and commitment to the process.

What the protocol addresses

  • Metabolic rate and insulin sensitivity
  • Hunger signaling and satiety dysregulation
  • Hormonal contributors to fat retention
  • Inflammatory burden affecting metabolic function
  • Thyroid and adrenal contributions to metabolic resistance

How it works

The protocol begins with a metabolic and hormone panel to identify underlying contributors to weight resistance. Based on those findings, the physician designs an intervention that may include GLP-1 receptor agonists, peptides targeting metabolic signaling, or other physician-supervised compounds.

This is not a one-size-fits-all program. The intervention is calibrated to your specific metabolic picture. Ongoing physician oversight is required throughout.

What to expect

  • Response varies significantly based on starting point and underlying biology
  • Clinically meaningful changes are typically observed at 8–16 weeks
  • Protocol adjustments are made based on clinical response and labs
  • Long-term success requires lifestyle integration alongside the protocol
Weight management pharmacotherapy carries potential side effects and contraindications. All interventions in this protocol category require thorough medical evaluation before initiation. This program does not offer weight loss medications without physician oversight.

Appearance & Composition

AESTHETICS

Clinical-grade skincare formulations designed for prevention and regeneration, physician-supervised topical protocols.

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Who this is for

The Aesthetics protocol is built around two distinct clinical scenarios: those in their 20s and 30s seeking prevention-focused skincare, and those in their mid-30s and beyond addressing established or emerging signs of aging.

We distinguish between a prevention-first approach and a regenerative approach based on where you are in the aging timeline. The protocol is prescribed accordingly.

What the protocol addresses

  • Collagen synthesis and dermal remodeling
  • Expression lines and fine wrinkles
  • Inflammaging and systemic skin inflammation
  • Cellular senescence and mitochondrial dysfunction
  • Skin barrier integrity and elasticity

Preventative Skincare

Designed for individuals in their 20s and 30s with prevention as the primary goal. This is antioxidant and signaling support before aging becomes a clinical issue.

  • Tier 1 (Basic): GHK-Cu 0.2% Liposomal. Antioxidant protection and baseline collagen signaling.
  • Tier 2 (Plus): Adds Argireline and Leuphasyl for dual-mechanism expression line targeting.

Topical Regenerative Stack

Designed for individuals in their mid-30s and beyond with established or emerging signs of aging. This is high-potency dermal regeneration supported by cellular repair and senescent cell clearance.

  • Tier 1 (Basic): GHK-Cu 0.5% Liposomal. High-potency dermal remodeling.
  • Tier 2 (Plus): Adds NAD+ 10% for mitochondrial energy and cellular repair.
  • Tier 3 (Advanced): Adds Glutathione and KPV for anti-inflammatory and antioxidant support.
  • Tier 4 (Premier): Adds Sirolimus 0.1% for senolytic therapy via mTOR inhibition.

How it works

All formulations are physician-prescribed, compounded to pharmaceutical standards, and supplied in 15mL bottles for twice-daily application (2 pumps daily = 4-week supply). The protocol begins with a physician consultation to assess your skin baseline, goals, and which program is appropriate for your age and presentation.

Topical formulations are optimized for stability and transdermal delivery. Your physician will monitor skin tolerance and efficacy at follow-up intervals.

What to expect

  • Skin tolerance period: first 4 weeks as your skin adapts to active formulations
  • Visible changes in skin texture and brightness: typically 8–12 weeks
  • Expression line softening and firmness improvements: 12+ weeks, progressive with continued use
  • Consistency is required. Results depend on daily application and protocol adherence.
All Aesthetics protocols require physician consultation and prescription. Topical formulations may cause initial irritation, redness, or sensitivity. This typically resolves within 2–4 weeks as tolerance develops. Pregnancy and certain medical conditions are contraindications. A telehealth consultation with a Kinetic Edge Health physician is required before any formulation is dispensed.

Start with your labs.

Every protocol begins with a physician-ordered lab panel. Your data tells us which stack, and how to design it.

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